How We Digitized Prenatal Screening for 15,000+ Patients per Year

The Problem

Centrum Prenatalni Diagnostiky (CPD) Brno is one of the leading prenatal diagnostics centers in the Czech Republic, performing first trimester screening for chromosomal abnormalities (Trisomy 21, 18, and 13) across multiple partner hospitals.

Before our engagement, the entire screening workflow was paper-based:

• Manual risk calculations — doctors used printed lookup tables to convert ultrasound measurements (NT, CRL) and biochemical markers (PAPP-A, Free Beta-hCG) into MoM values and risk scores
• Paper patient records — thousands of screening forms stored in physical filing cabinets, making retrieval slow and error-prone
• 30-minute report generation — each screening report required manual data entry, calculation, and formatting
• No centralized data — partner hospitals had no shared access to screening results or patient history
• Compliance risk — paper records made GDPR compliance and audit trails difficult to maintain

What We Built

We designed and developed a custom prenatal screening information system that replaced the entire paper-based workflow with a secure, modern web application. The system handles everything from patient registration to automated risk calculation and report generation.

Screening form interface — first trimester risk assessment module

Core features

• First trimester screening: Automated T21, T18, and T13 risk calculation based on maternal age, ultrasound measurements, and biochemical markers
• Ultrasound measurements input: Structured forms for NT (nuchal translucency), CRL (crown-rump length), PAPP-A, and Free Beta-hCG with automatic MoM (multiples of median) conversions
• Patient records management: Complete digital patient registry with medical history, previous screenings, and referral tracking
• Screening reports: One-click generation of standardized screening reports with all measurements, risk scores, and clinical recommendations
• Doctor notes: Structured and free-text notes attached to each screening, with full audit trail
• Referral doctor management: Directory of referring physicians across partner hospitals, with automated result notifications

Technical approach

• PHP backend: Robust server-side application handling complex medical calculations and data management
• Modern responsive UI: Clean, intuitive interface optimized for clinical workflows — works on desktop and tablet
• Secure medical data handling: Encrypted storage, role-based access control, and comprehensive audit logging
• GDPR compliance: Built-in consent management, data retention policies, and right-to-erasure support
• Multi-hospital architecture: Single system serving multiple partner locations with appropriate data isolation

The Impact

The system transformed how CPD Brno operates. What used to take 30 minutes of manual work per screening now takes under 5 minutes — the doctor enters measurements, the system calculates risk scores automatically, and generates a complete report with one click.

• 15,000+ screenings per year processed through the system with full digital records
• 85% reduction in report time — from 30 minutes to approximately 5 minutes per screening
• 5 partner hospitals connected to the centralized system with real-time access to results
• Complete elimination of paper records — all data digitized, searchable, and backed up
• Automated risk calculations replaced manual lookup tables, eliminating human calculation errors
• Full GDPR compliance with audit trails, access logs, and data retention management

Key Takeaway

Healthcare doesn't always need cutting-edge AI. Sometimes the biggest impact comes from replacing manual, paper-based processes with well-designed software that respects clinical workflows. The doctors at CPD Brno didn't want a disruption — they wanted their existing process, but faster, more reliable, and without the filing cabinets.

The key was building the system around how clinicians actually work. We spent time in the clinic, watched the screening process end-to-end, and designed every form and calculation flow to match their established medical protocols. That's why adoption was immediate — it felt like an upgrade, not a replacement.